2013 Edwin Bierman Award
The 2013 Edwin Bierman Award has been given to Joseph L. Witztum, MD. Given in memory Edwin L. Bierman, MD, an exemplary scientist, mentor and leader in the field of diabetes, obesity, hyperlipidemia and atherosclerosis, this award recognizes a leading scientist who has made outstanding contributions in the field of diabetes-related macrovascular complications and related risk factors.
Dr. Witztum is currently professor of medicine in the Department of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego. He is internationally recognized for his research into the pathogenesis of atherosclerosis, and in particular on the role of oxidized LDL in atherosclerotic lesions of experimental animals and man. His laboratory made the seminal observation that oxidation of LDL renders it immunogenic, and his team has played an important role in the recognition that immune mechanisms are an integral part of the atherogenic process. They have demonstrated that there are both adaptive and innate humoral and cellular immune responses to oxidized LDL that affect atherogenesis, suggesting novel therapeutic strategies.