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Predicting Low Blood GlucosePrediction of severe hypoglycemia, by D.J. Cox and colleagues. Diabetes Care 30:1370–1373, 2007 What is the problem and what is known about it so far?Although the goal of therapy for diabetes is to keep blood glucose levels as close to normal as possible, sometimes people slip into levels of blood glucose that are too low, known as hypoglycemia. Low blood glucose can cause changes in the level of consciousness or seizures, and should be avoided. Anticipating periods of low blood glucose is key to preventing problems. Why did the researchers do this particular study?The researchers wanted to see if there is a pattern to blood glucose levels that might signal when blood glucose is about to get too low. Who was studied?The study included 100 people with type 1 diabetes who were followed for 6 months and 79 people with type 2 diabetes who were followed for 4 months. How was the study done?All participants were given a glucose monitor to test their blood glucose levels at regular periods throughout the day. People with type 1 diabetes tested their blood glucose an average of 5.4 times per day, while those with type 2 diabetes tested an average of 3.5 times per day. What did the researchers find?Test results revealed a pattern of blood glucose levels about 24 hours before an episode of low blood glucose. The changes predicted hypoglycemia in about 60% of cases. What are the limitations of the study?Researchers don’t know if participants did something based on the glucose monitor that may change later test results. Hypoglycemia wasn’t predicted in every case, so the method may not be entirely reliable. What are the implications of the study?A pattern that is detectable by self-monitoring of blood glucose may predict when people are likely to have an episode of low blood glucose.
For more informationHypoglycemia Prevention and Treatment Diabetes Travel Guide, 2nd Edition
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