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Diabetes Therapy Reduces Fatty LiverWhat is the problem and what is known about it so far?A person who has diabetes is more likely to develop a fatty liver, known as hepatic steatosis. This condition can be very serious, often leading to scarring or cirrhosis of the liver. Studies show that nearly two-thirds of people with diabetes or high levels of blood glucose also have high levels of fats in the liver that may lead to fatty liver. Some research suggests that insulin may make fatty liver worse. Because the combo of insulin and metformin is often prescribed to people with diabetes, it is important to know whether these drugs add to fatty liver. Why did the researchers do this particular study?The researchers wanted to look at changes in liver fats when people start taking insulin and metformin. Who was studied?The study included 19 people with newly diagnosed diabetes who had not previously received treatment for diabetes. How was the study done?Participants had a physical exam and blood drawn for lab tests, including measurements of fats linked to fatty liver. Participants were prescribed doses of insulin and metformin to bring blood glucose back into normal ranges. Participants were checked on for 3 months of treatment. What did the researchers find?After 3 months, blood tests showed that fatty liver was reduced by nearly half, with 75% of participants having normal levels of fats in the bloodstream. What were the limitations of the study?The study was small, with a short follow-up period. A larger study with a longer follow-up period may show different results. What are the implications of the study?Treatment with a combination of insulin and metformin reduced fatty liver in people newly diagnosed with type 2 diabetes. FOR MORE INFORMATION
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