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Women With Type 2 Diabetes at Greater Risk for Cardiovascular Disease Than Men With Type 2 Diabetes


Normotensive women with type 2 diabetes and microalbuminuria are at high risk for macrovascular disease, by A.A.M. Zandbergen and colleagues. Diabetes Care 29:1851–1855, 2006


Why did the researchers do this particular study?


Heart and blood vessel (cardiovascular) disease is more common in people with type 2 diabetes, and it is more common in women with type 2 diabetes than in men with type 2 diabetes.

Who was studied?


Forty-six men and 21 women who had type 2 diabetes and microalbuminuria. The average age of the women was 54 years, and the average age of the men was 56 years. All of the patients had normal blood pressure when the study began.

Microalbuminuria is when small amounts of protein are present in the urine. It is a common diabetes complication and is an early sign of kidney damage (nephropathy).

How was the study done?


The researchers checked on the patients’ past medical records and performed a check-up, and they monitored the patients’ medication use, blood pressure, kidney function, and blood glucose levels for over 4 years on average.

What did the researchers find?


In this study, almost 40% of the women (8 of 21) developed cardiovascular problems by the end of the study; only 13% of the men (6 of 46) developed cardiovascular problems.

What are the limitations of the study?


At the beginning of the study, the women had higher blood pressure and a higher BMI (weight in relation to height) than the men. However, after adjusting for these differences, the women in this study still showed a higher risk for cardiovascular diseases.

This study included a relatively small number of patients.

What are the implications of the study?


In this study of people who had type 2 diabetes, microalbuminuria, and normal blood pressure, women had a higher risk of getting cardiovascular diseases than men. More studies are needed to determine why this is the case.

FOR MORE INFORMATION

Women & Diabetes

Kidney Disease (Nephropathy)

Diabetes: Heart Disease & Stroke

The Uncomplicated Guide to Diabetes Complications



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