Clinical Trials

A clinical trial is a way to carefully test a new drug or device in patients before it is approved by the FDA to be used in the general public. Clinical trials are an important step in our being able to have new treatments for diabetes and other conditions.

The American Diabetes Association is currently a partner providing support for the following clinical studies and initiatives:

TrialNet
Type 1 Diabetes TrialNet is an international network of researchers who are exploring ways to prevent, delay and reverse the progression of type 1 diabetes.

GRADE
GRADE is a comparative effectiveness study looking at what medications work best at lowering blood glucose levels in patients who are newly diagnosed with diabetes.

RISE
The Restoring Insulin Secretion study (RISE) includes 3 studies examining whether aggressive glucose lowering will lead to recovery of pancreas function in those with prediabetes and early type 2 diabetes.

D2d
The goal of the Vitamin D and type 2 diabetes (D2d) study is to determine whether vitamin D supplementation is safe and effective in delaying the onset of type 2 diabetes in people at risk for the disease, and to gain a better understanding of how vitamin D affects glucose metabolism.

Accelerating Medicines Partnership
The Accelerating Medicines Partnership (AMP) is a bold new venture between the NIH, non-profit organizations and biopharmaceutical companies to transform the current model for developing new diagnostics and treatments. By jointly identifying and validating promising biological targets of disease, the partnership strives to increase the number of new diagnostics and therapies for patients and reduce the time and cost of developing them.

FNIH Biomarkers Consortium
The Biomarkers Consortium is a public-private biomedical research partnership managed by the Foundation for the National Institutes of Health that endeavors to discover, develop, and qualify biological markers (biomarkers) to support new drug development, preventive medicine, and medical diagnostics.

Clinical Trials Links and Resources

By policy, the American Diabetes Association does not list or promote specific clinical trials other than the trials above in which it is a formal collaborator. This policy also applies to patient surveys. There are far too many trials and surveys being conducted at any given time for the Association to be able to evaluate them on an individual basis. However, the following resources from the Food and Drug Administration and the National Institutes of Health provide more information about clinical trials and how to determine which trials are being conducted in a location near you.

ClinicalTrials.gov
A registry and results database of federally and privately supported clinical trials conducted in the United States and around the world. ClinicalTrials.gov gives you information about a trial's purpose, who may participate, locations and phone numbers for more details.

National Institutes of Health (NIH)
The National Institutes of Health (NIH), a part of the U.S. Department of Health and Human Services, is the nation's medical research agency—making important discoveries that improve health and save lives.

Food and Drug Administration (FDA)
FDA is responsible for protecting the public health by assuring the safety, efficacy and security of human and veterinary drugs, biological products, medical devices, our nation's food supply, cosmetics, and products that emit radiation.

Centers for Medicare and Medicaid Service: Clinical Trials Coverage (CMS)

  • Last Reviewed: October 8, 2014
  • Last Edited: October 14, 2014

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