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News & Research
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Recent Advances Archive
November 30, 2011
Estrogen in the Brain Prevents Obesity in Women
ADA-funded researcher Yong Xu, MD, PhD, from the Baylor College of Medicine, has now uncovered the critical areas in the brain where estrogen acts through specific estrogen receptors, known as ER- to control metabolism, energy expenditure, and reproduction.
October 31, 2011
Saturated vs. Unsaturated: Why Some Fats are Healthier Than Others
A recent ADA-funded study conducted by Michael Karin, PhD and his postdoctoral fellow Debanjan Dhar, PhD from the University of California, San Diego, may help explain why saturated fat is more likely to cause insulin resistance and type 2 diabetes.
May 31, 2011
Changes in Amino Acid Levels Following Gastric Bypass May Improve Diabetes
Two American Diabetes Association-supported researchers have discovered potential clues that may help explain why gastric bypass surgery provides these beneficial effects independent of weight loss.
April 30, 2011
Insulin Signaling in the Brain Controls Fat Metabolism
American Diabetes Association-funded researcher Christoph Buettner, M.D., Ph.D., is the first to show that brain insulin signaling is a major regulator of fat metabolism.
October 31, 2010
Brain Hormones Regulate Diabetes and Female Fertility
Joel Elmquist, DVM, PhD and fellow Jong-Woo Sohn, PhD, study how leptin and insulin work together inside the hypothalamus and provide clues to female fertility and how type 2 diabetes can develop in the absence of obesity.
September 30, 2010
Serotonin and Dietary Protein Control Risk for Gestational Diabetes
American Diabetes Association-funded researcher Michael German, MD and his postdoctoral fellow, Hail Kim, MD, PhD, have discovered that serotonin is the key regulator of diabetes onset during pregnancy.
June 30, 2010
Critical Enzyme in Fat Metabolism Provides Protection against Diet-induced Insulin Resistance in Mice
American Diabetes Association-funded researcher Robert Farese, MD, in collaboration with other scientists from the J. David Gladstone Institutes, have shown that a specific enzyme may offer protection against the complications of excess body fat.
May 31, 2010
Diet, Exercise, Anti-Diabetic Drugs Can Delay or Prevent Type 2 Diabetes for 10+ Years
Association-funded researcher William C. Knowler, MD, DrPH, co-authored an article reporting the results of a 10-year follow-up Diabetes Prevention Program Outcomes Study (DPPOS) in participants from the original trial.
March 31, 2010
Beta Cell Function Regulated by Insulin in Healthy Humans
American Diabetes Association-funded researcher Allison Goldfine, MD (Career Development Award), has uncovered a surprising discovery about the production of insulin.
February 28, 2010
Links Between Immune System and Metabolism Uncovered
American Diabetes Association-funded researcher Gökhan Hotamisligil has published results specifically links inflammation, mediated by the immune system and metabolism.
January 31, 2010
Saving limbs using gene therapy and stem cells
Dr. Gregg Semenza, MD, PhD has published findings that could improve a common condition of diabetes called blood vessel blockage.
August 31, 2009
Promising Diabetic Retinopathy Treatment
With his Basic Science Award, Jian-xing (Jay) Ma, MD, PhD, has found a potential new treatment for diabetic retinopathy, a common complication of the eyes that can cause blindness in those with type 1 and type 2 diabetes.
June 30, 2009
Restoring Leptin Sensitivity in the Brain
Leptin, a hormone that is produced by fat cells, works through the brain to manage appetite and metabolism. Christian Bjorbaek, PhD, has published findings from his study that clarifies the mechanisms through which leptin works.
May 31, 2009
Study Suggests That Obesity-Prevention Efforts Should Begin Prior to Adolescence
A study by ADA-funded researcher Lisa Martin, PhD and colleagues, found that teenager’s weight and body mass index (BMI) tends to stay the same throughout adolescence.
April 30, 2009
Excess Fat Contributes to Cardiovascular Risks in Type 2 Diabetes
Guillermo Umpierrez, MD determined that free fatty acids (FFAs) in sustained high levels can contribute to the development of hypertension and inflammation in obese African-Americans.
January 31, 2009
Researchers identify a liver protein in mice regulated by fat content in diet
Dr. Butler and his fellow researchers identified a novel mechanism linking weight gain with insulin resistance in mice.
December 31, 2008
Researchers identify immune system educator cells outside of the thymus
James Gardner, an MD/PhD, identified a new type of cell that may be important in preventing autoimmune diseases like type I diabetes.
May 30, 2008
High Glucose Levels in Pregnant Women Lead to Pregnancy Complications Even in Non-Diabetic Ranges
Boyd E. Metzger, MD, examined whether complications in pregnancy can be associated with lower levels of hyperglycemia than the standards currently used to diagnose gestational diabetes.
March 31, 2008
Scientists Discover a Protein that Could Lead to Gestational Diabetes
A paper published in the journal Science this month reports that a protein known as menin appears to play a role in the development of diabetes in pregnant women.
February 28, 2008
Eleven genes identified in connection with cholesterol levels and coronary artery disease
Cristen Willer, PhD, a postdoctoral fellow training in the laboratory of Michael Boehnke, PhD, was lead author on a February 2008 paper published in Nature Genetics.
