Perfect, Michelle M., PhD
Elucidating the Role of Sleep in Glycemic Control and Neurobehavioral Functioning in Youth with Type 1 Diabetes
General Research Subject: Type 1 Diabetes
Focus: Other, Pediatrics, Pediatrics\Type 1, Psychosocial Behavioral Medicine
Type of Grant: Clinical Science and Epidemiology
Project Start Date: July 1, 2013
Project End Date: June 30, 2016
Diabetes Type: Type 1 diabetes
Despite research to support that sleep problems may affect how the body processes glucose and that individuals with diabetes report more sleep complaints than individuals without diabetes, current treatments do not consider the role of sleep in managing diabetes. Further, youth with T1DM often also experience learning and behavioral problems. These areas are also known to be affected by poor sleep quantity or quality. Thus, there is a pressing need to identify which aspects of sleep are most important in improving the health of youth with T1DM. Further, there is an urgency to test interventions to improve sleep that are efficient and feasible to help regulate glucose levels and improve cognition and behaviors for these youth.
The proposed study will ask youth with T1DM (ages of 10 through 16) to sleep as they usually do for six days. We will then ask youth to change their sleep based on one of two sets of instructions provided for another six days. During these weeks, participants will wear a sleep watch, have a sleep study conducted at their home for one night, and wear a continuous glucose monitor. At the end of both weeks, participants will complete assessments measuring memory, attention, and behavior. We will also obtain parent and teacher ratings. By asking these youth to modify their sleep for multiple days, we will be able to determine how sleep directly affects glucose, cognition, and behavior. These findings will be used to make recommendations for considering sleep in diabetes management.
What area of diabetes research does your project cover? What role will this particular project play in preventing, treating and/or curing diabetes?
The proposed study will provide an understanding of the role that sleep, particularly duration, plays in glycemic control and functioning in areas that are criticial to successful management of diabetes, such as memory, attention, reaction time, vigiliance, and behaviors. The experimental design will show if sleep directly impacts these areas.
If a person with diabetes were to ask you how your project will help them in the future,
how would you respond?
Getting more sleep could help them both biologically and psychologically; they may feel more alert and have more energy to manage their diabetes.
Why is it important for you, personally, to become involved in diabetes research? What role will this award play in your research efforts?
Diabetes very much involves self-care behaviors that if executed could lead to well-controlled glucose. Working with the families, it is evident that they want to be successful but current intense interventions are overwhelming for them. Sleep is essential to everyone and insufficient sleep is linked with a host of difficulties. Thus, targeting sleep may be the missing link in diabetes management,
In what direction do you see the future of diabetes research going?
Continued efforts to integrate sleep interventions in diabetes clinical care.
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