Horvath, Tamas Laszlo, DVM, PhD
Insulin determines developmental organization of hypothalamic circui
General Research Subject: Obesity
Focus: Insulin Action, Insulin Action\Transgenic Models, Integrated Physiology, Integrated Physiology\Regulation of Food Intake, Obesity, Obesity\Animal Models
Type of Grant: Mentor Based Postdoctoral Fellowship
Project Start Date: July 1, 2012
Project End Date: June 30, 2016
Type II diabetes has been called the plague of the 21st century. Emerging data suggest that overfeeding during pregnancy can have a long lasting influence on the child that can lead to the development of diabetes later in life. It is not known what the factors are during pregnancy that bring about these long lasting changes in the offspring. Our research focuses on this critical issue and will test specific hypotheses to develop therapeutic strategies to diminish the impact of perinatal events on diabetes development.
Mentor: Tamas Laszlo Horvath, DVM, PhD Postdoctoral Fellow: Luis Varela, PhD
What area of diabetes research does your project cover? What role will this particular project play in preventing, treating and/or curing diabetes?
My laboratory studies the central component of energy metabolism with particular interest in the role of the melanocortin system. In the project that is supported by ADA, we are attempting to understand how environmental factors affect the development of the hypothalamic controller of glucose metabolism and how maternal obesity may impact the development of metabolic impairments in the offspring. If successful, our project will inform on the negative or beneficial role of maternal metabolic status on vulnerability to childhood or adult onset metabolic disorders, including type 2 diabetes.
If a person with diabetes were to ask you how your project will help them in the future, how would you respond?
We will be able to advice pregnant women how to control their metabolic status to ensure prevention of vulnerability to develop diabetes in their children.
Why is it important for you, personally, to become involved in diabetes research? What role will this award play in your research efforts?
My expertise lies within the central regulation of peripheral energy metabolism and glucose utilization. To assure the my basic research projects have clinical relevance, I am eager to relate my studies to metabolic disorders, such as type 2 diabetes and obesity.
In what direction do you see the future of diabetes research going?
I believe that the future of diabetes care is in prevention.
Check out our parent mentor volunteer program full of parents just like you!
Become a Red Strider! Know someone with diabetes? Walk for them!
Every dollar you give can be doubled until May 15th to help Stop Diabetes!
Scroll through our calendar of EXPOs to find out when there will be one near you.
Ditch the chips! We've got recipes for eight healthy snacks you'll love to eat.
Learn what BIG discounts on auto insurance may await you.
Get motivated with our newly revised “I Hate to Exercise” book
Subscribe to our blog! It’s the best way to see what we’re up to at the Association.
If you have diabetes, join us for the ride!
Order your Diabetes Forecast® today! 25 Tips to healthy living. Click here to start.
Check out our site full of vegetarian meal planning ideas!
Find your local office to get involved in your community.
A new tool to increase the convenience of portion management
Get recipes, tips and more! Join the conversation!
Learn more about Dribble to Stop Diabetes