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Recent Advances
Learn about exciting recent advances attributable to American Diabetes Association-funded researchers.
October 31, 2012
Novel Insight on Fat Cell Regulation May Hold Key for Anti-Obesity Drugs
Association-funded researchers at the University of Michigan have recently shed light on important biological processes contributing to obesity and metabolic complications like diabetes.The discovery may explain why fat expands and metabolism slows as obesity progresses.
August 31, 2012
Chemicals in Popular Consumer Products Associated with Increased Risk of Diabetes in Women
Chemicals commonly found in beauty and hygiene products may increase the risk of diabetes in women. Tamarra James-Todd, PhD, and her mentor Janet Rich-Edwards, PhD, from Brigham and Women’s Hospital suggest that exposure to phthalates may be partially to blame for the growing prevalence of diabetes in women.
July 31, 2012
Accelerating Wound Closure in Patients with Diabetes
One of the most common complications associated with both type 1 and type 2 diabetes is delayed wound healing. If left untreated, wounds can lead to infection, amputation, and even death. Results from an ADA-funded study presented at the Association's 72nd Scientific Sessions introduced a novel treatment strategy that may significantly improve wound healing.
April 30, 2012
Diabetes May Originate in the Intestines
While the role of the pancreas and the liver in the development of diabetes are well described, a recent study conducted by ADA-funded researchers at Washington University in St. Louis suggests that the digestive system may also play a surprising and important role in developing the disease.
March 31, 2012
ADA Researcher Receives Top Award in Medicine
Congratulations to Philipp E. Scherer, PhD of the University of Texas Southwestern Medical Center for winning the 2012 Peter and Edith O’Donnell Award – the most prestigious honor in the field of medicine awarded in the state of Texas. Presented by The Academy of Medicine, Engineering and Science of Texas (TAMEST), the award recognizes Dr. Scherer’s exceptional accomplishment and contribution to research in diabetes and obesity.
February 29, 2012
Innovative Immune Cell Re-education Technique Holds Promise for Type 1 Diabetes
In 2010, the ADA funded an innovative research project lead by Yong Zhao, MD, PhD, who proposed a novel use for stem cells, derived from human umbilical cord blood, to overcome autoimmunity in patients with type 1 diabetes and ultimately reverse the disease.
January 31, 2012
Vera Novak: Type 2 Diabetes Deteriorates Brain Function
While the impact of diabetes on brain function is complex and poorly understood, Vera Novak, MD, PhD, has made novel clinical breakthroughs in this field of medicine and has established strong links between diabetes, inflammation, and blood flow within the brain. Furthermore, she has confirmed the correlation between the hallmarks of type 2 diabetes, brain atrophy and cognitive decline in aging adults.
November 30, 2011
Estrogen in the Brain Prevents Obesity in Women
ADA-funded researcher Yong Xu, MD, PhD, from the Baylor College of Medicine, has now uncovered the critical areas in the brain where estrogen acts through specific estrogen receptors, known as ER- to control metabolism, energy expenditure, and reproduction.
October 31, 2011
Saturated vs. Unsaturated: Why Some Fats are Healthier Than Others
A recent ADA-funded study conducted by Michael Karin, PhD and his postdoctoral fellow Debanjan Dhar, PhD from the University of California, San Diego, may help explain why saturated fat is more likely to cause insulin resistance and type 2 diabetes.
September 30, 2011
Laura Shin: Bone Marrow Stem Cells Hold Promise for Treating Diabetes-related Foot Complications
ADA-funded clinical scientist Laura Shin, from the Rosalind Franklin University of Medicine and Science, aspires to achieve an effective therapy for diabetic foot complications through the use of mesenchymal stem cells (MSCs), a type of stem cell that can be isolated from adult bone marrow.
July 31, 2011
Deborah Young-Hyman, PhD: Evaluating the Risk of Eating Disorders in Teenagers with Type 1 Diabetes
Association-funded project, Dr. Young-Hyman found that teens seeking insulin-pump therapy, an attractive treatment for those concerned about their weight, are more vulnerable to eating disorders.
June 30, 2011
Felicia Hill-Briggs, PhD and Frederick Brancati, MD, MHS: Intensive Problem-Solving Training Improves Diabetes Self-Management in Low-Income Patients
Populations stricken with poverty and low literacy rates face barriers in caring for their health, such as the inability to pay for medications, limited access to healthy foods, family care taking demands, and even neighborhood violence.
May 31, 2011
Changes in Amino Acid Levels Following Gastric Bypass May Improve Diabetes
Two American Diabetes Association-supported researchers have discovered potential clues that may help explain why gastric bypass surgery provides these beneficial effects independent of weight loss.
April 30, 2011
Insulin Signaling in the Brain Controls Fat Metabolism
American Diabetes Association-funded researcher Christoph Buettner, M.D., Ph.D., is the first to show that brain insulin signaling is a major regulator of fat metabolism.
March 31, 2011
Matthias von Herrath, MD: Software Accurately Predicts Optimization of Type 1 Diabetes Treatment
In a study published in the December 2010 issue of Diabetes, Matthias von Herrath, MD from the La Jolla Institute for Allergy and Immunology confirmed the accuracy of computer modeling in enhancing drug efficacy against type 1 diabetes.
February 28, 2011
Ian Gallicano, PhD: Sperm Stem Cells Hold Promise for Type 1 Diabetes Treatment
New research suggests that men with type 1 diabetes may be capable of generating their own insulin-producing cells for transplantation.
January 31, 2011
Frank Hu, MD, PhD, MPH: Sugar-Sweetened Beverages Increase Risk of Type 2 Diabetes and Metabolic Syndrome
An analysis conducted by an American Diabetes Association-funded researcher, Frank Hu, MD, PhD, MPH, shows that regular consumption of sugar-sweetened beverages is strongly associated with developing type 2 diabetes and metabolic syndrome.
October 31, 2010
Brain Hormones Regulate Diabetes and Female Fertility
Joel Elmquist, DVM, PhD and fellow Jong-Woo Sohn, PhD, study how leptin and insulin work together inside the hypothalamus and provide clues to female fertility and how type 2 diabetes can develop in the absence of obesity.
September 30, 2010
Serotonin and Dietary Protein Control Risk for Gestational Diabetes
American Diabetes Association-funded researcher Michael German, MD and his postdoctoral fellow, Hail Kim, MD, PhD, have discovered that serotonin is the key regulator of diabetes onset during pregnancy.
June 30, 2010
Johanna DiStefano, PhD: Genetic Markers for End-Stage Renal Disease in Type 1 Diabetes Identified
After observing a strong genetic influence in her research, Association-funded researcher Johanna K. DiStefano, aimed to identify genes that contribute to the development of the most debilitating and fatal condition of nephropathy, called end-stage renal disease (ESRD).
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