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Recent Advances

   

Learn about exciting recent advances attributable to American Diabetes Association-funded researchers.  

June 30, 2010
Critical Enzyme in Fat Metabolism Provides Protection against Diet-induced Insulin Resistance in Mice
American Diabetes Association-funded researcher Robert Farese, MD, in collaboration with other scientists from the J. David Gladstone Institutes, have shown that a specific enzyme may offer protection against the complications of excess body fat.

June 1, 2010
Sandeep Dhindsa, MD, and Paresh Dandona, MD: Obesity and Diabetes Lower Testosterone Levels in Men
The study shows that testosterone levels decline dramatically as weight-to-height ratio, or body-mass-index (BMI), increases.

May 31, 2010
Diet, Exercise, Anti-Diabetic Drugs Can Delay or Prevent Type 2 Diabetes for 10+ Years
Association-funded researcher William C. Knowler, MD, DrPH, co-authored an article reporting the results of a 10-year follow-up Diabetes Prevention Program Outcomes Study (DPPOS) in participants from the original trial.

April 30, 2010
Paresh Dandona, MD: Orange juice can help to reduce vascular inflammation
New data from Paresh Dandona, MD, at the University of Buffalo show that drinking orange juice with meals high in fats and carbohydrates helps to prevent blood vessel damage and reduces inflammatory stress.

March 31, 2010
Beta Cell Function Regulated by Insulin in Healthy Humans
American Diabetes Association-funded researcher Allison Goldfine, MD (Career Development Award), has uncovered a surprising discovery about the production of insulin.

February 28, 2010
Links Between Immune System and Metabolism Uncovered
American Diabetes Association-funded researcher Gökhan Hotamisligil has published results specifically links inflammation, mediated by the immune system and metabolism.

January 31, 2010
Saving limbs using gene therapy and stem cells
Dr. Gregg Semenza, MD, PhD has published findings that could improve a common condition of diabetes called blood vessel blockage.

January 31, 2010
Teresa Hillier, MD, MS: Ethnicity plays a role in the development of gestational diabetes for Chinese and Korean-Americans
Teresa Hillier, MD, MS found that more than 10% of women of Chinese and Korean heritage may be at risk for developing diabetes during pregnancy.

November 30, 2009
Vivian Fonseca, MD: Hurricane Katrina significantly impacted persons with diabetes
Dr. Vivian Fonseca, MD at Tulane University School of Medicine in New Orleans, LA studied the devastating impact of Hurricane Katrina on persons with diabetes.

September 30, 2009
Deborah Muoio, PhD: Glucose Intolerance Reversed
Deborah Muoio, PhD, found that providing obese rats with carnitine supplements helps them to clear the extra sugar they have trouble removing from their blood.

August 31, 2009
Promising Diabetic Retinopathy Treatment
With his Basic Science Award, Jian-xing (Jay) Ma, MD, PhD, has found a potential new treatment for diabetic retinopathy, a common complication of the eyes that can cause blindness in those with type 1 and type 2 diabetes.

July 31, 2009
Samuel Dagogo-Jack, MD: Obesity Study
Samuel Dagogo-Jack, MD, and his postdoctoral fellow, Nicoleta Ionica, MD, compared the indirect measure of body fat, BMI, to body fat directly measured in the same patient using DEXA.

June 30, 2009
Restoring Leptin Sensitivity in the Brain
Leptin, a hormone that is produced by fat cells, works through the brain to manage appetite and metabolism. Christian Bjorbaek, PhD, has published findings from his study that clarifies the mechanisms through which leptin works.

June 30, 2009
Eva Feldman, MD, PhD and Rodica Pop-Busui, MD, PhD: Elevated Triglyceride Levels and Nerve Loss
Eva Feldman, and Pop-Busui have found that elevated levels of triglycerides (stored fat used for energy) can be used as a predictor of nerve loss (neuropathy) in persons with diabetes.

May 31, 2009
Study Suggests That Obesity-Prevention Efforts Should Begin Prior to Adolescence
A study by ADA-funded researcher Lisa Martin, PhD and colleagues, found that teenager’s weight and body mass index (BMI) tends to stay the same throughout adolescence.

April 30, 2009
Excess Fat Contributes to Cardiovascular Risks in Type 2 Diabetes
Guillermo Umpierrez, MD determined that free fatty acids (FFAs) in sustained high levels can contribute to the development of hypertension and inflammation in obese African-Americans.

March 31, 2009
Gerald Shulman, MD, PhD: Blocking Gene Inhibits Insulin Resistance
An American Diabetes Association Distinguished Clinical Scientist Award recipient, Shulman was highlighted for his work related to the molecular mechanisms that are responsible for insulin resistance and type 2 diabetes.

January 31, 2009
Drs. Hollie Raynor, Rena Wing and Chantelle Hart : Early Eating and Activity Habits could contribute to Childhood Obesity
ADA-funded researchers Drs. Hollie Raynor, Rena Wing and Chantelle Hart investigated the eating and activity patterns of children ages 2 to 12.

January 31, 2009
Researchers identify a liver protein in mice regulated by fat content in diet
Dr. Butler and his fellow researchers identified a novel mechanism linking weight gain with insulin resistance in mice.

December 31, 2008
Researchers identify immune system educator cells outside of the thymus
James Gardner, an MD/PhD, identified a new type of cell that may be important in preventing autoimmune diseases like type I diabetes.

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