Patient Access to Research

Patient Informs logoPicture of a couple looking at the computerpatientINFORM is a program that provides patients with access to research on the diagnosis and treatment of specific diseases.

Select a topic below to view digests of late-breaking research published in respected medical journals on diabetes and related conditions. These digests are intended to help you understand the latest research. The information provided is not a substitute for advice from your doctor or other health care provider.

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 Most recently published digests:

March 17, 2015
Making Breakfast the Biggest Meal May Help Control Glucose All Day
Eating the largest meal of the day at breakfast and the smallest at dinner may help people with type 2 diabetes to better control their blood glucose. Although this study focused on short-term effects, routinely following such a diet could lower A1C and reduce the risk of heart and blood vessel diseases and other complications.

March 17, 2015
Eyes on the Prize: Studying the Frequency of Eye Exams for Patients With Differing Retinopathy Risks
This study supports the possibility of putting people with diabetes into different risk categories based on the degree of retinopathy they have and safely recommending less or more frequent eye exams accordingly. Under such a plan, people with low risk could get an eye exam perhaps every 2 years, whereas those with high risk could have exams twice yearly, and those with moderate risk could get annual exams. Such a plan could reduce the burden on patients and save on health care costs.

March 15, 2015
Are Children With Type 1 Diabetes at Increased Risk for Mental Illness?
Children with type 1 diabetes are at high risk for mental health problems. The finding that those born earlier had a higher risk than those born later suggests that advances in diabetes care that allow for more flexible lifestyles and eating habits have helped to reduce this risk. Because siblings of children with type 1 diabetes have mental illnesses at about the same rate as the general population, the higher risk for those with diabetes seems to stem from having the disease rather than from genetic factors or their family environment. This study highlights the need for thorough mental health screening of children with type 1 diabetes, especially those who have been recently diagnosed.

February 12, 2015
Many Older Veterans With Diabetes and Dementia May Have Tighter Glucose Control Than Is Safe
Many older veterans with diabetes and dementia are at high risk for hypoglycemia associated with intense glucose control. More than half of this population has tight control even though a more relaxed level of control is recommended. Of those with tight control, three-fourths take medicines that have a high risk of hypoglycemia. These individuals may be candidates for a less-intense glucose control regimen to increase their safety.

February 12, 2015
Peel, Stick, Check: Glucose-Sensing "Tattoo" Could One Day Replace Finger-Prick Testing
With more work, products such as the glucose-sensing tattoo could do away with the need for finger-prick blood testing for many people with diabetes.

February 12, 2015
Take Heart: Study Finds No Higher Risk of Heart Failure From Incretin-Based Diabetes Medicines
The results of this study provide some reassurance of the heart safety of incretin-based medicines for diabetes. However, they will need to be replicated in other large studies.

January 28, 2015
Stepping It Up: Treating Diabetic Foot Infections May Take Half as Long as Previously Thought
Six weeks of antibiotics may be enough to successfully treat people with DFO who have not had surgery.

January 28, 2015
Cell Service: Gene Therapy Causes β-Cell Growth and Reversal of Type 1 Diabetes in Mice
This type of research, while still in an early stage, suggests that new approaches to curing type 1 diabetes through gene therapy may be possible in the future.

January 28, 2015
Molecular Research Provides a Close-Up View of How Proteins Move Glucose from Blood to Cells
Research such as this, which focuses on the shape and function of proteins in the body, could pave the way for the development of new drugs. For example, by understanding how GLUT proteins work to move glucose into cells, scientists can develop drugs that speed up that process (to treat high blood glucose) or slow it down (to treat low blood glucose) in people with diabetes.

January 13, 2015
Type 2 Diabetes Remission Without Surgery Does Happen—But Very Rarely
Type 2 diabetes remission can occur in people who have not had weight loss surgery, but it is very, very rare. Applying the results of this study to the entire 25.6 million Americans with type 2 diabetes suggests that 384,000 people could have some type of remission in the next 7 years. However, only 1,800 people would have a remission lasting at least 5 years.


The structured summary format used by patientINFORM was developed by the Annals of Internal Medicine, which regularly includes patient summaries of research articles.


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