Archive of Recent Advances
Exciting advances attributable to American Diabetes Association-funded researchers from previous years.
November 7, 2014
A Close-Up View of Glucose Transport
Association-funded researcher Dr. Tamir Gonen recently published a critical study that provides the information needed to design new diabetes drugs. But it almost didn’t happen.
October 31, 2014
A Genetic Link to Type 2 Diabetes in Obesity
Although obesity is known to be a significant risk factor for developing type 2 diabetes, most obese people never develop diabetes. An Association-funded researcher aims to understand what factors contribute to diabetes risk in the setting of obesity.
September 25, 2014
Reducing Cardiovascular Disease Risk in Youth with Type 1 Diabetes
While insulin resistance is known to contribute to cardiovascular disease in type 2 diabetes, its role in type 1 diabetes has been less clear. Association-funded researcher Dr. Kristen Nadeau aims to understand how to reduce cardiovascular complications in type 1 diabetes.
August 12, 2014
Progress in Artificial Pancreas Development: Preventing and Treating Low Blood Glucose
An important limitation to development of an artificial pancreas is the danger of low blood glucose caused by insulin infusion. A recent study links automated glucagon delivery-to combat low blood glucose-to automated insulin delivery to overcome this issue and bring artificial pancreas technology closer to reality.
July 15, 2014
Diet During Pregnancy Affects Offspring Later in Life
A number of studies connects conditions in the womb to the health of the offspring. A recent study shows that a high-fat diet during pregnancy and lactation makes offspring suffer increased negative effects of high-fat diet as adults. Interestingly, these effects are not linked to inherited genes.
July 1, 2014
Testing Vitamin D for Heart Health in Type 2 Diabetes
Produced in the body in response to sunlight, vitamin D is crucial for everything from strong bones to heart health. Modern life has made vitamin D deficiency more common. Type 2 diabetes also makes it harder for the body to produce vitamin D. Association-funded researcher Dr. Carlos Bernal-Mizrachi is conducting an experiment to see if correcting vitamin D deficiency can slow or halt the progression of cardiovascular disease.
June 30, 2014
Type 2 Diabetes Gene Acts through Neighboring Pancreas Cells
Beta cells in the pancreas are known to secrete insulin to regulate blood glucose. A recent study shows that one gene linked to type 2 diabetes actually works in the delta cell, a neighboring cell type within the pancreas, which helps “remotely” control insulin and glucagon production in beta and alpha cells, respectively.
June 1, 2014
Bone and Joint Health in Type 1 Diabetes
Bones seem like the one feature of our bodies that doesn't move or change. But unlikely as it may seem, the 206 bones in your body are actually a lifelong work in progress: Every seven years, give or take, you get a new skeleton. Association-funded researcher Dr. Shannon Wallet is working to find out why diabetes people with diabetes have much more bone breakdown than normal.
May 30, 2014
Uncovering a New Key to Increased Heart Disease Risk in Diabetes
People with diabetes have double the risk of heart attack and stroke. A recent series of studies reveals how insulin resistance leads the walls of arteries to become thicker and increases stroke risk, as well as how an existing diabetes medication works to counteract this risk.
February 28, 2014
The Obesity Paradox - Does Excess Weight Improve Survival?
How is body weight linked to death rates among people with type 2 diabetes? Recent studies have surprisingly suggested longer life for overweight or obese people with type 2 diabetes. However, a new study provides a more conclusive answer to this puzzling question.
January 31, 2014
Mother's Diet Affects Brain Development and Metabolism in Offspring
New evidence suggests that the environment in the womb has long lasting effects on the offspring. One recent study shows how a mother’s diet during pregnancy affects risk for obesity and diabetes in offspring through changes in brain development.
May 31, 2013
Methane-producing Bacteria in Gut May Increase Risk for Diabetes
ADA-funded investigator Ruchi Mathur, MD is exploring a possible link between microorganisms found in the gut and an increased risk of developing obesity and diabetes.
February 28, 2013
Vitamin D Deficiency May Contribute to Clogged Arteries in People with Type 2 Diabetes
In a recent Association-supported study, investigator Carlos Bernal-Mizrachi, MD, at Washington University School of Medicine in St. Louis, has found that low levels of vitamin D may play a causal role in atherosclerosis in people with type 2 diabetes.