Type 1 Research Highlights

Type 1 Research Highlights

While the Association’s priority is to improve the lives of all people affected by diabetes, type 1 diabetes is a critical focus of the organization. In fact, in 2016, 37 percent of our research budget was dedicated to projects relevant to type 1 diabetes. Read more about the critical research made possible by the American Diabetes Association.

Smart Insulin Patch Developed by Dr. Zhen Gu

Developing New Technology for Continuous Glucose Monitoring

Dr. Zhou has led the development and testing of materials called hybrid nanogels to serve as probes that can accurately sense glucose concentrations.

Schematic of immune interaction

Targeting the Autoimmune Response to Prevent Type 1 Diabetes

Dr. Piganelli is looking for ways to prevent type 1 diabetes by interrupting the autoimmune process.

immune complex

Targeting the Autoimmune Response to Prevent Type 1 Diabetes

Dr. Piganelli is looking for ways to prevent type 1 diabetes by interrupting the autoimmune process.

Explore: Type 1 Research Highlights

  • Investments in Type 1 Diabetes Research

    About 1.25 million Americans have type 1 diabetes and an estimated 40,000 people will be newly diagnosed each year in the U.S. The American Diabetes Association funds a productive research portfolio that offers significant progress and hope for improved outcomes for people with type 1 diabetes.

  • Identifying Type 1 Diabetes before Beta Cell Loss

    Dr. Hessner is investigating so-called “biomarkers,” which are components in blood or tissue samples that can be measured to predict which individuals are most likely to develop type 1 diabetes.

  • Targeting the Autoimmune Response to Prevent Type 1 Diabetes

    Dr. Piganelli is looking for ways to prevent type 1 diabetes by interrupting the autoimmune process.

  • Beta Cell Replacement

    Both type 1 and type 2 diabetes result from a complete or partial loss of beta cell number and function. Finding a way to successfully replace functional beta cell is key to efforts to one day cure diabetes.

  • Enhancing Survival of Beta Cells for Successful Transplantation

    Islet transplantation has long offered hope as a curative measure for type 1 diabetes. However, more than 80% of transplanted islets die within one week after transplantation. Research efforts are working to improve their survival and the promise of stem cells to reverse diabetes.

  • Developing New Technology for Continuous Glucose Monitoring

    Dr. Zhou has led the development and testing of materials called hybrid nanogels to serve as probes that can accurately sense glucose concentrations.

  • Improving Technology to Save Eyesight

    Dr. Jayagopal is leading a study to develop targeted therapy for retinopathy that would recognize and deliver therapy only to diseased tissue.